Disease Research Ion channels play a role in many diseases, including hypertension, cardiac arrhythmias, gastrointestinal, immune and neuromuscular disorders, pathological pain and cancer. Fast, reproducible application switching Quick Select Feature recalls up to three saved amplifier configurations. Order To order the Multiclamp B amplifier please Call us at: Automated optimization features; reduction of manipulation steps; and convenient; reliable telegraphing. Leak subtraction for automatic correction of leak currents with a smart, software-based algorithm. Thank you Your quote request has been received and we will be in touch shortly.

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Software control of all amplifier settings Automated optimization features; reduction of manipulation steps; and multcilamp reliable telegraphing. This control interface reports resistance, voltage, and current measurements and provides automation of Bridge Balance, Pipette Offset, and Pipette Capacitance Neutralization for improved ease of use. A critical part of drug discovery involves safety assessments, such as hERG testing, in order to eliminate any compounds with potential safety concerns.

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Leak subtraction for automatic correction of leak currents with a smart, software-based algorithm. Products Electrophysiology Rigs Other Required Components Amplifiers and DAQ Amplifiers Mutliclamp Devices MultiClamp B Amplifier A microelectrode amplifier that combines leading edge electronics design and a wealth of features and functions with an intuitive user interface that simplifies the creation of complex protocols.

Axon™ MultiClamp™ Commander Software Download page

Major new features of the MultiClamp B Amplifier include Internal Automatic Mode switching, triggered by external signals or the recording itself; Oscillation Suppression for better cell protection; and Slow Current Injection to compensate for drifting potentials. Happy holidays from all of the team at Scientifica!

Benefits Additional Information Specifications. Easy monitoring of membrane and cell health parameters Integrated seal test in voltage- and current-clamp mode. Thank you Your quote request has been received and we will be in touch shortly.

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Ion channels multiclmap pore proteins that are involved in a large variety of physiological processes. A microelectrode amplifier that combines leading edge electronics design and a wealth of features and functions with an intuitive user interface that simplifies the creation of complex protocols.

Ion channels play a role in many diseases, including multticlamp, cardiac arrhythmias, gastrointestinal, immune and neuromuscular disorders, pathological pain and cancer. For single-channel recordings, whole-cell voltage- and current-clamp recordings, intracellular sharp electrode recordings, extracellular field potential recordings in ion multiclapm, neuroscience, nanopore and voltammetry studies. Ion channels are involved in many cell pathways and understanding the function of ion channels in response to changes in membrane potential or the presence or absence of other molecules is important in order to understand exactly how ion channels participate in normal and abnormal biological processes such as cell differentiation and migration, disease states, neuronal communications, etc.

Automatic pipette capacitance compensation milticlamp only the push of a button to neutralize the contribution of the glass pipette and the pipette holder to the capacitance of the circuitry. If you consent to us collecting and storing your data from this form please tick the checkbox below.

Automatic correction Leak subtraction for automatic correction of leak currents with a smart, software-based algorithm.

Automated optimization features; reduction of manipulation steps; and convenient; reliable telegraphing. This ensures that the amplifier settings are accurately and conveniently stored in the recorded data files. Pipette offset compensation with auto-mode quickly removes signal offsets.

Molecular Devices MultiClamp B Amplifier

Prediction helps achieve the desired command level faster by transiently supercharging the membrane potential. To order the Multiclamp B amplifier please Multiclajp us at: Correction improves the bandwidth of the recording by eliminating the error introduced by the voltage drop across the series resistance.

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Fine tunable 4-pole bessel and butterworth low-pass filters act as anti-aliasing filters and can be used to pre-condition the output signal. Automatic oscillation detection prevents damage to a cell when electrical feedback nulticlamp.

MultiClamp 700B

Rack use Standard 19″ rack-mount 2U with handles. By understanding the exact role that ion channels play in a particular disease, researchers might be able to find a way to affect the ion channel in such a way as to alter the course of the disease. Cell Pathway Analysis Ion channels are involved in many cell pathways and understanding the function of ion channels in response to changes in membrane potential or the presence or absence of other molecules is important in order to understand exactly how ion channels participate in normal and abnormal biological processes such as cell differentiation and migration, disease states, neuronal communications, etc.

Add two more optional headstage voltage-follower inputs for a four-point recording system, ideal for complex synaptic recordings. Computer control of the amplifier ensures correct scaling and logging of experimental parameters.

External Control Automatic mode switching enables you to control the transition between voltage and current clamp by an external trigger or depending on the recorded signal. Specifications General Specifications Dimensions in. Dual Command Potential Add flexibility by processing input signals from two different sources. Basic research in the ion channel field furthers the understanding of ion channel function as well as their roles within cellular pathways and processes.

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